"Since prednisone is used in much higher doses than the levels of corticosteroids produced naturally by the body, but they most often are used for their potent anti-inflammatory effects, particularly in those conditions in which the immune system plays an important role. Prednisone and Prednisolone are considered to be intermediate acting steroids, meaning that a dose lasts about a day or a day and a half."
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"Prednisone is used as replacement therapy in patients whose adrenal glands are unable to produce sufficient amounts of cortical. Prednisolone works by acting within cells to prevent the release of substances in the body. Prednisolone is a corticosteroid medicine."