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Once-daily Valtrex is also the only medication proven to reduce the amount of time for an outbreak if taken soon enough. Valtrex has shown promise as a treatment for infectious mononucleosis and is preventatively administered in suspected cases of herpes virus exposure. It is prescribed. Valaciclovir is most effective when taken within 24 hours of the start of symptoms.

"It is not known if Valtrex prevents the spread of the herpes virus family. Valaciclovir is most effective if it is started within 48 hours of when the rash first appears. You will be immune to them for the rest of their life. Valaciclovir is a drug, an esterified version of aciclovir that has greater oral bioavailability than aciclovir."