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Antibotic bactrim:

Baclofen can be taken with or without food. Baclofen inhibits both monosynaptic and polysynaptic reflexes at the spinal level, probably by hyperpolarization of afferent terminals, although actions at supraspinal sites may also occur. Lioresal has the effect of the drug peaks two hours after each dose and is gone within five hours, so it is best to schedule doses for shortly before the daily activities when relief of spasticity is most important. Bactrim should be stored in at a room temperature.

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