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Both Neurontin and Topamax are prescribed off-label, which means that there is anecdotal evidence enough to prescribe them for this use. One of the medications that have been increasingly prescribed as a migraine preventive is the antiseizure medication Topamax. Topamax is used to prevent migraine headaches. Topiramate is an anticonvulsant used with other medicines to control certain types of seizures. It may increase the risk of seizures. Topiramate is prescribed for epilepsy, but it also is used to prevent migraine headaches.
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