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Deltasone may not work as effectively in people with liver disease whose ability to convert prednisone to Prednisolone is impaired. Prednisolone is a corticosteroid medicine. Prednisolone is commonly used for several days before the needed effect is achieved. Steroid drug is used to reduce inflammation and alleviate symptoms in a variety of disorders, including rheumatoid arthritis and severe cases of asthma.

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"A more potent mineral corticoid is administered concomitantly. Prednisolone is a corticosteroid used to treat various inflammatory and allergy conditions as well as other diseases. Your steroid medication needs may change if you have a fungal infection anywhere in your body."

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Prednisolone works by acting within cells to prevent the release of substances in the body and, in order to be effective, first must be converted to Prednisolone by enzymes in the liver. Before the needed effect is achieved. Prednisone is used in the management of adrenal insufficiency unless a more potent mineral corticoid is administered concomitantly.