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"Time each day. Metabolism of Tamsulosin may be slower, and older patients may be more sensitive to the orthostatic hypotension caused by this medication. Tamsulosin relaxes the muscles in the prostate and bladder neck at the site of the obstruction, resulting in an improvement in urine flow rate and a reduction in symptoms ofBPH."

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"Topiramate is an anticonvulsant used with other medicines to control certain types of seizures. The prevention of migraine headaches in adults. If you are using Topiramate to control epilepsy and you stop taking this medicine suddenly it may increase the risk of seizures. Topamax is indicated for the prophylaxis of migraine headaches has not been studied."