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Celebrex is safe unless you are allergic to Celecoxib, aspirin or other NSAIDs may experience an allergic reaction to Celecoxib and should not take Celecoxib. If you are allergic to it or to sulfa drugs. Celebrex treats inflammation by preventing the body's synthesis of a chemical called prostaglandin. Celecoxib differs from other anti-inflammatory drugs in that it causes less inflammation and ulceration of the stomach and intestine and does not interfere with the clotting of blood.

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