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Treatment should be started with a beta-blocker rather than a diuretic. Beta-blockers work by blocking beta receptors that are found in various parts of the body. Propranolol reduces the workload of the heart and so decreases its demand for oxygen. There may be an increased risk of slow heart rate. The combination of Propranolol with thiazide-like diuretics and peripheral vasodilators has been shown to be compatible and generally more effective than Propranolol alone. Several reports in the published literature describe cases in which Propranolol was used as a suicide agent.
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