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How to take premarin: "In women with ovarian failure or other conditions that cause a lack of natural estrogen in the body. If you are taking antidepressants or a thyroid medication. If you are taking antidepressants or a thyroid medication. Because estrogens have been linked with an increased risk of breast cancer, heart attack, and certain estrogen-dependent cancers, contact your doctor right away if you notice sudden shortness of breath or abnormal bleeding from the vagina
