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"Several reports in the published literature describe cases in which Propranolol was used as a suicide agent. Possible deleterious effects from long-term use of Propranolol have not yet been adequately appraised. If Propranolol is taken with calcium channel blockers such as verapamil, nifedipine or diltiazem, there may be an increased risk of slow heart rate, tremor and nausea."