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Fluconazole has been associated with birth defects when given at high doses early in a pregnancy. If you experience any of the serious side effects, stop taking Diflucan right away. Fluconazole has been used in the fungal infection Cryptococcus. Do not stop taking Diflucan without developing too many side effects you got are too bothersome, you can report them to you health care provider to decide about the way you will be supposed to take Fluconazole.