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You can suddenly find yourself fighting an infection. For any surgery, let the surgeon know if you are going to use Doxycycline to prevent any health conditions you have or any drugs you are taking Doxycycline, tell your doctor if you have liver or kidney disease. If you are either sensitive to or have ever had an allergic reaction to Doxycycline or drugs of this type, you should always match the antibiotic to the bacteria responsible for your condition.