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Prednisone is the most commonly-prescribed oral corticosteroid. Do not stop using Prednisolone suddenly, or you could have unpleasant withdrawal symptoms. Prednisolone is a corticosteroid medicine. Do not stop using Prednisolone suddenly, or you could have unpleasant withdrawal symptoms. Prednisolone is used for treating several types of arthritis systemic lupus, allergic reactions, asthma and severe psoriasis.