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A more potent mineral corticoid is administered concomitantly. Your steroid medication needs may change if you have any of these conditions, you may need a dose adjustment or special tests to safely take Prednisolone. Deltasone may not work as effectively in people with liver disease whose ability to convert prednisone to Prednisolone is impaired. Do not stop using Prednisolone suddenly, or you could have unpleasant withdrawal symptoms. Prednisolone is commonly used for several days before the needed effect is achieved.
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