Accutane used for acne present for many years that has not responded completely to antibiotics. Accutane works to achieve partial or complete clearance of acne in about everyone who completes a cycle, regardless of whether they have inflammatory or non-inflammatory acne. Astringents, rubbing alcohol, and tanning do not help clear acne nor keep acne-prone skin free from blemishes. Depending on your reaction to Accutane, your doctor will monitor you closely during Accutane therapy. Acne such as acne conglobata.