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Clopidogrel should be used with caution. While you are taking Clopidogrel. A recent study has shown that patients receiving aspirin plus the proton pump inhibitor Esomeprazole had a lower incidence of recurrent ulcer bleeding than patients receiving Clopidogrel. Plavix, or Clopidogrel bisulfate, include bleeding and, rarely, low white blood cell counts and low platelet counts with spontaneous bleeding and clotting. While you are taking Clopidogrel, do not take aspirin, ibuprofen or naproxen without your doctor's advice.