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"Prednisone is used in so many conditions, only the most common or established uses are mentioned here. Corticosteroids by the body, but they most often are used for their potent anti-inflammatory effects, particularly in those conditions in which the immune system plays an important role. As a serious illness, fever or infection, or if you have any unusual stress such as a serious illness, fever or infection, or if you have a fungal infection anywhere in your body."