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Your symptoms. Celecoxib is used for treating rheumatoid arthritis, and gout. Celecoxib should only be used in pregnant women when the benefits outweigh the potential risk to the fetus. Celecoxib acts as an anti-inflammatory, analgesic and anti-pyretic agent by blocking the action of a substance in the body by inhibiting the breakdown of Celecoxib in the body called cyclo-oxygenase.

"Fluconazole increases the concentration of Celecoxib in the body by inhibiting the breakdown of Celecoxib in the liver. This medication can increase your risk of serious side effects on the stomach or intestines, including bleeding or perforation. When taking Celebrex, it is important to keep taking it as instructed by your doctor."

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