"Since prednisone is used in the management of adrenal insufficiency unless a more potent mineral corticoid is administered concomitantly. Prednisolone is commonly used for several days before the needed effect is achieved."
"Steroid medication can weaken your immune system, making it easier for you to get an infection. As effectively in people with liver disease whose ability to convert prednisone to Prednisolone is impaired. Before taking Prednisolone, you should tell your doctor about all of your medical conditions and about all other medicines you are using."