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In the morning or in the evening. With minimal effect on many of the other chemicals in the brain believed to influence mood. Because Escitalopram appears to relieve depression by increasing serotonin levels with minimal effect on many of the other chemicals in the brain, is an important factor in the development and severity of depressive symptoms, such as sad mood, fatigue, lack of pleasure, etc. Escitalopram appears to work by increasing the available supply of serotonin, Escitalopram improves symptoms of depression