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Differences of only a few micrograms of Synthroid can make a large difference in how you feel. Most commonly prescribed of all the thyroid supplements. You need to be observant of possible side effects for this reason the correct dose of Synthroid is difficult to find. Thyroid gland does not produce enough thyroid hormone. Synthroid may cause seizures at the beginning of treatment, although this is rare. Some hair, but this effect is usually temporary. Most of these problems disappeared when levothyroxine tablets were taken with water.